GHK-Cu is a copper peptide your body naturally produces. It plays a key role in skin repair, collagen production, and protecting your cells from everyday damage. As you age, your levels drop — and that's when you start to notice slower healing, thinner skin, and more visible signs of aging.
Three amino acids. Thirty-one percent of human genes. Here’s how copper peptide signaling supports regeneration across multiple biological systems.

GHK-Cu is a copper-binding peptide studied for its potential role in collagen synthesis, skin regeneration, anti-aging support, and neuroprotection. It may influence approximately 31% of human genes involved in tissue repair and aging. Available as subcutaneous injection, scalp foam, and facial cream. At iThriveMD, your provider evaluates your specific goals to determine whether GHK-Cu may be appropriate for you.
The standard protocol at iThriveMD is 2.5 mg (50 units) via subcutaneous injection, administered 5 days per week 3 months on and 1 month off. Dosing is always determined by your prescribing provider based on your individual health profile and goals.
The most common side effects are mild: injection site redness, localized swelling, and transient discomfort. GHK-Cu affects copper-zinc balance, which is why zinc supplementation is required. In rare cases, patients may experience blue lunula (nail discoloration), erythema, or rash. Individuals with Wilson’s disease or copper metabolism disorders should not use GHK-Cu. Your provider will assess your risk factors.
Research suggests GHK-Cu may support collagen and elastin production, provide antioxidant protection against oxidative stress, promote wound healing and tissue repair, support hair growth, and offer neuroprotective benefits.
Results are cumulative and vary based on application and individual factors. Some patients report improvements in skin texture and tone within several weeks of consistent use. Hair growth support may take longer. Your provider monitors your progress and adjusts your protocol as needed.
Yes. At iThriveMD, all peptide therapy requires a medical evaluation and a provider prescription. GHK-Cu is prepared in our sterile cleanroom facility and is not available over the counter.
